Neurobiology of Disease Involvement of the Thalamic Parafascicular Nucleus in Mesial Temporal Lobe Epilepsy
نویسندگان
چکیده
Mélanie Langlois,1 Pierre-Olivier Polack,3 Hélène Bernard,1 Olivier David,2 Stéphane Charpier,3 Antoine Depaulis,1 and Colin Deransart1 1Equipe 9, Dynamique des Réseaux Synchrones Epileptiques, and 2Equipe 5, Neuroimagerie Fonctionnelle et Métabolique, Grenoble Institut des Neurosciences, Institut National de la Santé et de la Recherche Médicale U 836-Université Joseph Fourier-Commisariat à l’Energie Atomique Centre Hospitalier Universitaire, 38700 La Tronche, France, and 3Centre de Recherche de l’Institut du Cerveau et de la Moelle Épinière, Université Pierre et Marie Curie/Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche-S 975, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7225, Hôpital Pitié-Salpêtrière, 75013 Paris, France
منابع مشابه
Involvement of the thalamic parafascicular nucleus in mesial temporal lobe epilepsy.
Mesial temporal lobe epilepsy (MTLE) is characterized by focal seizures, associated with hippocampal sclerosis, and often resistance to antiepileptic drugs. The parafascicular nucleus (PF) of the thalamus is involved in the generation of physiological oscillatory rhythms. It receives excitatory inputs from the cortex and inhibitory inputs from the basal ganglia, a system implicated in the contr...
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Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies. Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...
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